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Concept information

Preferred term

Glomerulosclerosis, Focal Segmental  

Type

  • mesh:Descriptor

Definition

  • A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE. Segmental glomerular degeneration with a glassy appearance (hyalinosis) caused by the accumulation of plasma proteins in the glomeruli.

Broader concept

Entry terms

  • Focal Segmental Glomerulosclerosis
  • Glomerulonephritis, Focal Sclerosing
  • Glomerulosclerosis, Focal

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-B09J82L5-M

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