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... > Polycyclic Compounds > Fused-Ring Compounds > Steroids > Pregnanes > Pregnenes > Cortisone
... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Hormones, Hormone Substitutes, and Hormone Antagonists > Hormones > Adrenal Cortex Hormones > Hydroxycorticosteroids > 17-Hydroxycorticosteroids > Cortisone

Preferred term

Cortisone  

Type

  • mesh:Descriptor

Definition

  • A naturally occurring glucocorticoid that has been used in replacement therapy for ADRENAL INSUFFICIENCY and as an anti-inflammatory agent. Cortisone itself is inactive; it is converted in the liver to the active metabolite HYDROCORTISONE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726) The acetate ester of cortisone that is used mainly for replacement therapy in adrenocortical insufficiency and in the treatment of many allergic and inflammatory disorders.

Broader concept

Entry terms

  • 29253-51-8 (former CAS registry number)
  • 50-04-4 (Cortisone Acetate)
  • 53-06-5 (Cortisone)
  • 883WKN7W8X
  • Pregn-4-ene-3,11,20-trione, 17,21-dihydroxy-
  • V27W9254FZ

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • Cortisone

    French

  • 29253-51-8 (former CAS registry number)
  • 50-04-4 (Cortisone Acetate)
  • 53-06-5 (Cortisone)
  • 883WKN7W8X
  • Pregn-4-ene-3,11,20-trione, 17,21-dihydroxy-
  • V27W9254FZ

URI

http://data.loterre.fr/ark:/67375/JVR-B16ZCCG2-P

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