Concept information
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Intracellular Signaling Peptides and Proteins
Protein Serine-Threonine Kinases
Mitogen-Activated Protein Kinases
Extracellular Signal-Regulated MAP Kinases
Preferred term
Mitogen-Activated Protein Kinase 1
Type
-
mesh:Descriptor
Definition
- A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme by phosphorylation leads to its translocation into the nucleus where it acts upon specific transcription factors. p40 MAPK and p41 MAPK are isoforms.
Broader concept
Entry terms
- Extracellular Signal-Regulated Kinase 2
- MAPK1 Mitogen-Activated Protein Kinase
- MAPK2 Mitogen-Activated Protein Kinase
- MAP Kinase 2
- Mitogen-Activated Protein Kinase 2
- p42 MAPK
- p42(Mapk)
- p42 MAP Kinase
- p42(Mapk) Kinase
- p42(Mitogen-Activated Protein Kinase)
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
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French
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ERK-2
-
ERK2
-
Extracellular Signal-Regulated Kinase 2
-
Kinase-2 régulée par un signal extracellulaire
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MAP-kinase-2
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MAP-kinase-p42
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MAPK1 Mitogen-activated protein kinase
-
MAPK2 Mitogen-activated protein kinase
-
P42 MAPK
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P42 mitogen-activated protein kinase
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p42(Mitogen-activated protein kinase)
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Protein-kinase Mk1
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Protéine-kinase-1 activée par les agents mitogènes
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Protéine-kinase-1 activée par les facteurs mitogènes
-
Protéine-kinase-2 activée par les facteurs mitogènes
-
Protéine-kinase-2 régulée par des signaux extracellulaires
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Protéine-kinase-p42 activée par les mitogènes
URI
http://data.loterre.fr/ark:/67375/JVR-B1C9KKFQ-T
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