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Concept information

Preferred term

Supranuclear Palsy, Progressive  

Type

  • mesh:Descriptor

Definition

  • A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)

Entry terms

  • Palsy, Progressive Supranuclear
  • Progressive Supranuclear Palsy
  • Richardson's Syndrome
  • Steele-Richardson-Olszewski Disease
  • Steele-Richardson-Olszewski Syndrome

In other languages

  • French

  • Maladie de Steele-Richardson-Olszewski
  • Maladie de Steele-Ridcharson
  • Ophtalmoplégie supranucléaire
  • Ophtalmoplégie supranucléaire progressive
  • PSP (Paralysie Supranucléaire Progressive)
  • Syndrome de Steele-Richardson-Olszewski

URI

http://data.loterre.fr/ark:/67375/JVR-B27CPK4X-X

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