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... > Neoplasms > Neoplasms by Histologic Type > Neoplasms, Glandular and Epithelial > Neoplasms, Neuroepithelial > Neuroectodermal Tumors, Primitive > Neuroectodermal Tumors, Primitive, Peripheral > Neuroblastoma
... > Neoplasms > Neoplasms by Histologic Type > Neoplasms, Germ Cell and Embryonal > Neuroectodermal Tumors > Neoplasms, Neuroepithelial > Neuroectodermal Tumors, Primitive > Neuroectodermal Tumors, Primitive, Peripheral > Neuroblastoma
... > Neoplasms > Neoplasms by Histologic Type > Neoplasms, Nerve Tissue > Neuroectodermal Tumors > Neoplasms, Neuroepithelial > Neuroectodermal Tumors, Primitive > Neuroectodermal Tumors, Primitive, Peripheral > Neuroblastoma

Preferred term

Neuroblastoma  

Type

  • mesh:Descriptor

Definition

  • A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

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http://data.loterre.fr/ark:/67375/JVR-BB5CC910-T

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