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... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structural Elements > Amino Acid Motifs > Helix-Loop-Helix Motifs > Helix-Turn-Helix Motifs > ETS Motif
... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structure, Secondary > Amino Acid Motifs > Helix-Loop-Helix Motifs > Helix-Turn-Helix Motifs > ETS Motif

Preferred term

ETS Motif  

Type

  • mesh:Descriptor

Definition

  • A helix-turn-helix motif characterized by three alpha-helices and four-stranded beta-sheets arranged in the order alpha1-beta1-beta2-alpha2-alpha3-beta3-beta4. The third alpha-helix contacts the major groove of DNA. The ETS motif and the flanking amino acid sequences of Ets proteins influence the binding affinity, and the alteration of a single amino acid in the Ets domain can change its DNA binding specificity.

Broader concept

Related concepts

Entry terms

  • ETS Domain
  • Helix-Turn-Helix, ETS-Type Domain Containing

Allowable Qualifier(s)

In other languages

  • Motif ETS

    French

  • Domaine de type ETS contenant un motif hélice-tour-hélice
  • Domaine ETS

URI

http://data.loterre.fr/ark:/67375/JVR-BBCM324K-0

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RDF/XML TURTLE JSON-LD Created 7/8/16, last modified 5/9/16