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Concept information

Nucleic Acids, Nucleotides, and Nucleosides > Nucleosides > Deoxyribonucleosides > Pentostatin
Carbohydrates > Glycosides > Nucleosides > Deoxyribonucleosides > Pentostatin
... > Nucleic Acids, Nucleotides, and Nucleosides > Nucleosides > Ribonucleosides > Formycins > Coformycin > Pentostatin
... > Carbohydrates > Glycosides > Nucleosides > Ribonucleosides > Formycins > Coformycin > Pentostatin
... > Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Pyrimidines > Pyrimidine Nucleosides > Formycins > Coformycin > Pentostatin
... > Nucleic Acids, Nucleotides, and Nucleosides > Nucleosides > Pyrimidine Nucleosides > Formycins > Coformycin > Pentostatin
... > Carbohydrates > Glycosides > Nucleosides > Pyrimidine Nucleosides > Formycins > Coformycin > Pentostatin

Preferred term

Pentostatin  

Type

  • mesh:Descriptor

Definition

  • A potent inhibitor of ADENOSINE DEAMINASE. The drug induces APOPTOSIS of LYMPHOCYTES, and is used in the treatment of many lymphoproliferative malignancies, particularly HAIRY CELL LEUKEMIA. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.

Broader concept

Entry terms

  • 395575MZO7
  • 53910-25-1 (Pentostatin)
  • Imidazo(4,5-d)(1,3)diazepin-8-ol, 3-(2-deoxy-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (8R)-

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • Pentostatine

    French

  • 395575MZO7
  • 53910-25-1 (Pentostatin)
  • Imidazo(4,5-d)(1,3)diazepin-8-ol, 3-(2-deoxy-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (8R)-

URI

http://data.loterre.fr/ark:/67375/JVR-BCHX5J78-3

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RDF/XML TURTLE JSON-LD Created 5/25/89, last modified 7/1/19