Concept information
Preferred term
Proto-Oncogene Proteins c-mdm2
Type
-
mesh:Descriptor
Definition
- An E3 UBIQUITIN LIGASE that interacts with and inhibits TUMOR SUPPRESSOR PROTEIN P53. Its ability to ubiquitinate p53 is regulated by TUMOR SUPPRESSOR PROTEIN P14ARF.
Broader concept
Entry terms
- c-mdm2 Proto-Oncogene Protein
- Double Minute 2 Protein
- Mdm-2 Protein
- Mdm2 Protein
- MDMX Protein
- Murine Double Minute 2 Protein
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Protéine du proto-oncogène c-mdm2
-
Protéine mdm-2
-
Protéine mdm2
-
Protéine MDMX
URI
http://data.loterre.fr/ark:/67375/JVR-BG00SJ00-G
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