Concept information
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Membrane Proteins
Receptors, Cell Surface
Receptor Protein-Tyrosine Kinases
Receptors, Vascular Endothelial Growth Factor
...
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
Receptors, Vascular Endothelial Growth Factor
...
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
Receptors, Vascular Endothelial Growth Factor
Preferred term
Vascular Endothelial Growth Factor Receptor-1
Type
-
mesh:Descriptor
Definition
- A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction.
Broader concept
Entry terms
- FLT1 Receptor Tyrosine Kinase
- FLT1 RTK
- fms-Like Tyrosine Kinase
- Proto-Oncogene Protein flt
- VEGFR-1
- VEGF Receptor, FLT
- VEGF Receptor flt-1 Protein
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
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French
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FLT1 RTK
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Récepteur à tyrosine kinase FLT1
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Récepteur de type 1 au facteur de croissance des cellules endothéliales
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Récepteur de type 1 du facteur de croissance endothéliale vasculaire
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Récepteur de type I du facteur de croissance endothéliale vasculaire
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Récepteur-1 du facteur croissance endothéliale vasculaire
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Récepteur-1 du facteur de croissance de l'endothélium vasculaire
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Récepteur-1 du facteur de croissance des cellules endothéliales
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Tyrosine kinase apparentée à fms
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VEGFR-1
URI
http://data.loterre.fr/ark:/67375/JVR-BHZF3K35-W
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