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Metabolism > RNA Processing, Post-Transcriptional > RNA 3' End Processing > Polyadenylation
Chemical Phenomena > Biochemical Phenomena > RNA Processing, Post-Transcriptional > RNA 3' End Processing > Polyadenylation
Genetic Phenomena > Gene Expression Regulation > RNA Processing, Post-Transcriptional > RNA 3' End Processing > Polyadenylation

Preferred term

Polyadenylation  

Type

  • mesh:Descriptor

Definition

  • The addition of a tail of polyadenylic acid (POLY A) to the 3' end of mRNA (RNA, MESSENGER). Polyadenylation involves recognizing the processing site signal, (AAUAAA), and cleaving of the mRNA to create a 3' OH terminal end to which poly A polymerase (POLYNUCLEOTIDE ADENYLYLTRANSFERASE) adds 60-200 adenylate residues. The 3' end processing of some messenger RNAs, such as histone mRNA, is carried out by a different process that does not include the addition of poly A as described here.

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URI

http://data.loterre.fr/ark:/67375/JVR-BJ1N3XRF-3

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RDF/XML TURTLE JSON-LD Created 7/25/01, last modified 6/23/16