Concept information
Preferred term
Baclofen
Type
-
mesh:Descriptor
Definition
- A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission.
Broader concept
Entry terms
- 1134-47-0 (Baclofen)
- Baclophen
- Benzenepropanoic acid, beta-(aminomethyl)-4-chloro-
- beta-(Aminomethyl)-4-chlorobenzenepropanoic Acid
- beta-(p-Chlorophenyl)-gamma-aminobutyric Acid
- Chlorophenyl GABA
- H789N3FKE8
- PCP-GABA
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
1134-47-0 (Baclofen)
-
Benzenepropanoic acid, beta-(aminomethyl)-4-chloro-
-
bêta-4-chlorophényl-GABA
-
H789N3FKE8
-
PCP-GABA
URI
http://data.loterre.fr/ark:/67375/JVR-BKMFQ6DG-H
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