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... > Organic Chemicals > Amines > Quaternary Ammonium Compounds > Bis-Trimethylammonium Compounds > Hexamethonium Compounds > Hexamethonium
... > Inorganic Chemicals > Nitrogen Compounds > Ammonium Compounds > Quaternary Ammonium Compounds > Bis-Trimethylammonium Compounds > Hexamethonium Compounds > Hexamethonium
... > Organic Chemicals > Onium Compounds > Quaternary Ammonium Compounds > Bis-Trimethylammonium Compounds > Hexamethonium Compounds > Hexamethonium

Preferred term

Hexamethonium  

Type

  • mesh:Descriptor

Definition

  • A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.

Broader concept

Entry terms

  • 16986-49-5 (dichloride dihydrate)
  • 1,6-hexanediaminium, N,N,N,N',N',N'-hexamethyl-
  • 2079-78-9 (bitartrate)
  • 3C9PSP36Z2
  • 5187-74-6 (dibromide dihydrate)
  • 556-81-0 (dihydroxide)
  • 55-97-0 (dibromide)
  • 56503-18-5 (dimethylsulfate)
  • 60-25-3 (chloride)
  • 60-26-4 (Hexamethonium)
  • 78995-78-5 (diperchlorate)
  • 815-76-9 (monotartrate)
  • 870-62-2 (diiodide)
  • 8J77X3S603
  • G2753KSN40
  • Hexonium
  • TIV4Q933FU

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • Hexaméthonium

    French

  • 1,6-hexanediaminium, N,N,N,N',N',N'-hexamethyl-
  • 16986-49-5 (dichloride dihydrate)
  • 2079-78-9 (bitartrate)
  • 3C9PSP36Z2
  • 5187-74-6 (dibromide dihydrate)
  • 55-97-0 (dibromide)
  • 556-81-0 (dihydroxide)
  • 56503-18-5 (dimethylsulfate)
  • 60-25-3 (chloride)
  • 60-26-4 (Hexamethonium)
  • 78995-78-5 (diperchlorate)
  • 815-76-9 (monotartrate)
  • 870-62-2 (diiodide)
  • 8J77X3S603
  • G2753KSN40
  • N,N,N,N',N',N'-Hexaméthyl-hexane-1,6-diaminium
  • N,N,N,N',N',N'-Hexaméthylhexane-1,6-diaminium
  • TIV4Q933FU

URI

http://data.loterre.fr/ark:/67375/JVR-BL16PZ5M-Z

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