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Nervous System Diseases > Neuromuscular Diseases > Neuromuscular Junction Diseases > Myasthenia Gravis > Lambert-Eaton Myasthenic Syndrome
Immune System Diseases > Autoimmune Diseases > Autoimmune Diseases of the Nervous System > Myasthenia Gravis > Lambert-Eaton Myasthenic Syndrome
Nervous System Diseases > Autoimmune Diseases of the Nervous System > Myasthenia Gravis > Lambert-Eaton Myasthenic Syndrome
Nervous System Diseases > Nervous System Neoplasms > Paraneoplastic Syndromes, Nervous System > Myasthenia Gravis > Lambert-Eaton Myasthenic Syndrome
... > Neoplasms > Neoplasms by Site > Nervous System Neoplasms > Paraneoplastic Syndromes, Nervous System > Myasthenia Gravis > Lambert-Eaton Myasthenic Syndrome
Nervous System Diseases > Neurodegenerative Diseases > Paraneoplastic Syndromes, Nervous System > Myasthenia Gravis > Lambert-Eaton Myasthenic Syndrome
Neoplasms > Paraneoplastic Syndromes > Paraneoplastic Syndromes, Nervous System > Myasthenia Gravis > Lambert-Eaton Myasthenic Syndrome

Preferred term

Lambert-Eaton Myasthenic Syndrome  

Type

  • mesh:Descriptor

Definition

  • An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471)

Broader concept

Entry terms

  • Eaton-Lambert Myasthenic Syndrome
  • Eaton-Lambert Syndrome
  • Lambert-Eaton Syndrome
  • Myasthenic-Myopathic Syndrome of Eaton-Lambert
  • Myasthenic-Myopathic Syndrome of Lambert-Eaton
  • Myasthenic Syndrome, Lambert-Eaton
  • Myopathic-Myasthenic Syndrome of Eaton-Lambert
  • Myopathic-Myasthenic Syndrome of Lambert-Eaton

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-C0549M2Q-1

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