Concept information
Preferred term
Inositol 1,4,5-Trisphosphate
Type
-
mesh:Descriptor
Definition
- Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin.
Broader concept
Entry terms
- 1,4,5-InsP3
- 1,4,5-IP3
- 85166-31-0
- D-myo-Inositol, 1,4,5-tris(dihydrogen phosphate)
- Inositol 1,4,5-Triphosphate
- Myoinositol 1,4,5-Triphosphate
- Myo-Inositol 1,4,5-Trisphosphate
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
1,4,5-IP3
-
85166-31-0
-
D-myo-Inositol, 1,4,5-tris(dihydrogen phosphate)
-
Inositol 1,4,5 triphosphate
-
Inositol 1,4,5-tris(phosphate)
-
Myo-inositol 1,4,5-tris(phosphate)
-
Myo-inositol 1,4,5-trisphosphate
URI
http://data.loterre.fr/ark:/67375/JVR-C9H6D3P1-1
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