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Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > B7 Antigens > B7-1 Antigen
Biological Factors > Antigens > Antigens, Surface > B7 Antigens > B7-1 Antigen
Biological Factors > Intercellular Signaling Peptides and Proteins > B7 Antigens > B7-1 Antigen
Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > B7 Antigens > B7-1 Antigen
Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > B7 Antigens > B7-1 Antigen

Preferred term

B7-1 Antigen  

Type

  • mesh:Descriptor

Definition

  • A costimulatory ligand membrane glycoprotein that contains a V2 type and C2 IMMUNOGLOBULIN DOMAIN and is expressed by ANTIGEN-PRESENTING CELLS. It binds to CTLA-4 ANTIGEN with high specificity and to CD28 ANTIGEN with low specificity. The interaction of CD80 with CD28 ANTIGEN provides a costimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.

Broader concept

Related concepts

Entry terms

  • Antigen, B7-1
  • Antigens, CD80
  • B7-1 Costimulatory Molecule
  • B7-1 Ligand
  • B-Cell Activation Antigen
  • CD80 Antigen
  • CD80 Antigens

Allowable Qualifier(s)

In other languages

  • Antigène CD80

    French

  • Antigène B7-1
  • Antigène CD80 d'activation des lymphocytes B
  • CD80
  • Ligand B7-1
  • Molécule co-stimulante B7-1
  • Molécule costimulante B7-1
  • Molécule de co-stimulation B7-1
  • Molécule de costimulation B7-1

URI

http://data.loterre.fr/ark:/67375/JVR-CBT0PFHP-Q

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RDF/XML TURTLE JSON-LD Created 6/4/93, last modified 5/24/17