Concept information
Preferred term
Macroautophagy
Type
-
mesh:Descriptor
Definition
- The segregation of large parts of the cytoplasm, including ORGANELLES and PROTEIN AGGREGATES, into AUTOPHAGOSOMES and lysosomal degradation after fusion with LYSOSOMES. Macroautophagic degradation of PEROXISOMES. In yeast peroxisomes are degraded via a microautophagic process known as MICROPEXOPHAGY. Autophagic degradation of microorganisms in the CYTOPLASM. A selective type of macroautophagy in which PROTEIN AGGREGATES that are bound to chaperone HSPPA8 and other co-chaperones are taken in for lysosomal degradation by invagination. It is distinguished from CHAPERONE-MEDIATED AUTOPHAGY. Autophagic degradation of damaged LYSOSOMES. Macroautophagic degradation of PROTEASOMES.
Broader concept
Entry terms
- Macro-Autophagy
Allowable Qualifier(s)
In other languages
-
French
URI
http://data.loterre.fr/ark:/67375/JVR-CCDBVBBT-Z
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