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... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Caspases > Caspases, Initiator > Caspase 1
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > Caspases > Caspases, Initiator > Caspase 1
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Cysteine Proteases > Cysteine Endopeptidases > Caspases > Caspases, Initiator > Caspase 1
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Cysteine Endopeptidases > Caspases > Caspases, Initiator > Caspase 1

Preferred term

Caspase 1  

Type

  • mesh:Descriptor

Definition

  • A long pro-domain caspase that has specificity for the precursor form of INTERLEUKIN-1BETA. It plays a role in INFLAMMATION by catalytically converting the inactive forms of CYTOKINES such as interleukin-1beta to their active, secreted form. Caspase 1 is referred as interleukin-1beta converting enzyme and is frequently abbreviated ICE.

Broader concept

Related concepts

Entry terms

  • CASP1 Caspase
  • ICE Protease
  • IL1BC Enzyme
  • IL-1 beta Convertase
  • IL-1 beta-Converting Enzyme
  • Interleukin-1beta Converting Enzyme
  • Interleukin-1 Converting Enzyme

Allowable Qualifier(s)

In other languages

  • Caspase-1

    French

  • Caspase 1
  • Caspase CASP1
  • Cystéine protéase ICE
  • IL-1 beta Convertase
  • Interleukin-1 converting enzyme
  • Interleukin-1beta converting enzyme
  • Protéase ICE
  • Protéine ICE

URI

http://data.loterre.fr/ark:/67375/JVR-CCKNLHRV-R

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RDF/XML TURTLE JSON-LD Created 6/10/98, last modified 5/21/21