Concept information
Amino Acids, Peptides, and Proteins
Peptides
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Preferred term
Syk Kinase
Type
-
mesh:Descriptor
Definition
- An SH2 domain-containing non-receptor tyrosine kinase that regulates signal transduction downstream of a variety of receptors including B-CELL ANTIGEN RECEPTORS. It functions in both INNATE IMMUNITY and ADAPTIVE IMMUNITY and also mediates signaling in CELL ADHESION; OSTEOGENESIS; PLATELET ACTIVATION; and vascular development.
Broader concept
Entry terms
- Spleen Tyrosine Kinase
- SYK Tyrosine Kinase
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Kinase Syk
-
Tyrosine kinase de la rate
-
Tyrosine kinase SYK
URI
http://data.loterre.fr/ark:/67375/JVR-CCX7DW85-F
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