Concept information
Preferred term
Multiple Endocrine Neoplasia Type 2b
Type
-
mesh:Descriptor
Definition
- Similar to MEN2A, it is also caused by mutations of the MEN2 gene, also known as the RET proto-oncogene. Its clinical symptoms include medullary carcinoma (CARCINOMA, MEDULLARY) of THYROID GLAND and PHEOCHROMOCYTOMA of ADRENAL MEDULLA (50%). Unlike MEN2a, MEN2b does not involve PARATHYROID NEOPLASMS. It can be distinguished from MEN2A by its neural abnormalities such as mucosal NEUROMAS on EYELIDS; LIP; and TONGUE, and ganglioneuromatosis of GASTROINTESTINAL TRACT leading to MEGACOLON. It is an autosomal dominant inherited disease.
Broader concept
Entry terms
- MEA 2b
- MEA IIb
- MEN 2b
- MEN2b
- MEN 3
- MEN IIb
- MEN III
- Mucosal Neuroma Syndrome
- Multiple Endocrine Neoplasia, Type 2b
- Multiple Endocrine Neoplasia, Type IIb
- Multiple Endocrine Neoplasms Type 2b
- Neoplasia, Multiple Endocrine Type 2b
- Neoplasms, Multiple Endocrine Type 2b
- Neuromata, Mucosal, With Endocrine Tumors
- Wagenmann-Froboese Syndrome
Allowable Qualifier(s)
- blood (Qualifier)
- blood supply (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemically induced (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- complications (Qualifier)
- congenital (Qualifier)
- diagnosis (Qualifier)
- diagnostic imaging (Qualifier)
- diet therapy (Qualifier)
- drug therapy (Qualifier)
- economics (Qualifier)
- embryology (Qualifier)
- enzymology (Qualifier)
- epidemiology (Qualifier)
- ethnology (Qualifier)
- etiology (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- metabolism (Qualifier)
- microbiology (Qualifier)
- mortality (Qualifier)
- nursing (Qualifier)
- parasitology (Qualifier)
- pathology (Qualifier)
- physiopathology (Qualifier)
- prevention & control (Qualifier)
- psychology (Qualifier)
- radiotherapy (Qualifier)
- rehabilitation (Qualifier)
- secondary (Qualifier)
- surgery (Qualifier)
- therapy (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
- veterinary (Qualifier)
- virology (Qualifier)
In other languages
-
French
-
Adénomatose endocrinienne multiple de type 2b
-
NEM 2b
-
NEM IIb
-
NEM2b
-
Polyadénomatose endocrinienne de type 2B
URI
http://data.loterre.fr/ark:/67375/JVR-CJJN6M5M-Q
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}