Concept information
Preferred term
Autophagy
Type
-
mesh:Descriptor
Definition
- The segregation and degradation of various cytoplasmic constituents via engulfment by MULTIVESICULAR BODIES; VACUOLES; or AUTOPHAGOSOMES and their digestion by LYSOSOMES. It plays an important role in BIOLOGICAL METAMORPHOSIS and in the removal of bone by OSTEOCLASTS. Defective autophagy is associated with various diseases, including NEURODEGENERATIVE DISEASES and cancer. Lysosomal degradation of ENDOPLASMIC RETICULUM by MACROAUTOPHAGY or MICROAUTOPHAGY. Lysosomal degradation of RIBOSOMES. Lysosomal degradation of LIPID DROPLETS.
Broader concept
Narrower concepts
Entry terms
- Autophagocytosis
- Autophagy, Cellular
Allowable Qualifier(s)
In other languages
-
French
-
Autophagie cellulaire
-
Autophagocytose
URI
http://data.loterre.fr/ark:/67375/JVR-CPZC58HM-4
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}