Concept information
Amino Acids, Peptides, and Proteins
Peptides
Intracellular Signaling Peptides and Proteins
Protein Serine-Threonine Kinases
Preferred term
MAP Kinase Kinase Kinases
Type
-
mesh:Descriptor
Definition
- Mitogen-activated protein kinase kinase kinases (MAPKKKs) are serine-threonine protein kinases that initiate protein kinase signaling cascades. They phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES; (MAPKKs) which in turn phosphorylate MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs).
Broader concept
Narrower concepts
Entry terms
- Kinases, MAP Kinase Kinase
- MAP3 Kinase
- MAP3 Kinases
- MAP Kinase Kinase Kinase
- MAPKKK
- MAPKKKs
- Mitogen-Activated Protein Kinase Kinase Kinase
- Mitogen-Activated Protein Kinase Kinase Kinases
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
MAP3 Kinases
-
MAP3K
-
MAPKKK
-
Mitogen-Activated Protein Kinase Kinase Kinases
URI
http://data.loterre.fr/ark:/67375/JVR-CS56KQ6Q-R
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