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... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Metalloendopeptidases > Collagenases > Microbial Collagenase
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Metalloproteases > Metalloendopeptidases > Collagenases > Microbial Collagenase

Preferred term

Microbial Collagenase  

Type

  • mesh:Descriptor

Definition

  • A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.

Broader concept

Entry terms

  • Clostridiopeptidase A
  • Clostridium histolyticum Collagenase
  • Collagenase Clostridium histolyticum
  • Collagenase, Microbial
  • Collalysine
  • Nucleolysin

Allowable Qualifier(s)

In other languages

  • Microbial collagenase

    French

  • Clostridiopeptidase A
  • Clostridium histolyticum collagenase
  • Collagénase A
  • Collagénase I
  • Collalysine
  • Nucléolysine

URI

http://data.loterre.fr/ark:/67375/JVR-CW84FW0K-L

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