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Concept information

Preferred term

Survivin  

Type

  • mesh:Descriptor

Definition

  • An apoptosis inhibitory protein that contains a single baculoviral IAP repeat (BIR) domain. It associates with MICROTUBULES and functions to regulate cell proliferation as a component of the chromosome passage protein complex (CPC), performing essential roles for localization of the complex, chromosome alignment, segregation during MITOSIS and CYTOKINESIS, and assembly of the MITOTIC SPINDLE. It is expressed by fetal kidney and liver cells and highly expressed in ADENOCARCINOMA and high-grade LYMPHOMA.

Entry terms

  • Baculoviral IAP Repeat-containing Protein 5
  • BIRC5 Protein

In other languages

  • French

  • Protéine BIRC5
  • Protéine-5 contenant des répétitions IAP baculovirales

URI

http://data.loterre.fr/ark:/67375/JVR-CWG596FK-H

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RDF/XML TURTLE JSON-LD Created 7/9/18, last modified 1/16/18