Concept information
Preferred term
Receptor, Notch3
Type
-
mesh:Descriptor
Definition
- A notch receptor characterized by a large extracellular domain containing 34 EPIDERMAL GROWTH FACTOR-like repeats. It functions to regulate CELL DIFFERENTIATION; APOPTOSIS; and CELL PROLIFERATION. Mutations in the EGF repeats of Notch-3 are associated with CADASIL.
Broader concept
Entry terms
- Neurogenic Locus Notch Homolog Protein 3
- Notch-3 Protein
- Notch3 Protein
- Notch-3 Receptor
- Notch3 Receptor
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- physiology (Qualifier)
- radiation effects (Qualifier)
- therapeutic use (Qualifier)
- ultrastructure (Qualifier)
In other languages
-
French
-
Protéine du locus neurogénique-3 homologue de Notch
-
Protéine Notch-3
-
Protéine Notch3
-
Récepteur Notch-3
URI
http://data.loterre.fr/ark:/67375/JVR-D1N0SK25-N
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