Concept information
Preferred term
Methimazole
Type
-
mesh:Descriptor
Definition
- A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.
Broader concept
Entry terms
- 1-Methyl-2-mercaptoimidazole
- 2H-Imidazole-2-thione, 1,3-dihydro-1-methyl-
- 554Z48XN5E
- 60-56-0 (Methimazole)
- Mercasolyl
- Mercazolyl
- Merkazolil
- Methylmercaptoimidazole
- Methymazol
- Thiamazole
- Thimazol
- Tiamazol
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
2H-Imidazole-2-thione, 1,3-dihydro-1-methyl-
-
554Z48XN5E
-
60-56-0 (Methimazole)
-
Thiamazole
URI
http://data.loterre.fr/ark:/67375/JVR-D987WSK0-0
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