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Concept information

Preferred term

Oncogene Protein gp140(v-fms)  

Type

  • mesh:Descriptor

Definition

  • Transforming glycoprotein coded by the fms oncogene from the Susan McDonough strain of feline sarcoma virus (SM-FeSV). The oncogene protein v-fms lacks sequences, which, in the highly homologous proto-oncogene protein c-fms (CSF-1 receptor), normally serve to regulate its tyrosine kinase activity. The missing sequences in v-fms mimic the effect of ligand and lead to constitutive cell growth. The protein gp120(v-fms) is post-translationally modified to generate gp140(v-fms).

Entry terms

  • fms Oncogene Product gp140
  • fms Oncogene Protein gp140
  • gp140 v-fms
  • gp140(v-fms)
  • v-fms Protein

In other languages

  • French

  • gp140(v-fms)
  • Produit gp140 de l'oncogène fms
  • Protéine gp140 de l'oncogène fms
  • Protéine gp140(v-fms)
  • Protéine v-fms

URI

http://data.loterre.fr/ark:/67375/JVR-DC900V18-L

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RDF/XML TURTLE JSON-LD Created 6/19/90, last modified 5/24/19