Concept information
Preferred term
Carvedilol
Type
-
mesh:Descriptor
Definition
- A carbazole and propanol derivative that acts as a non-cardioselective beta blocker and vasodilator. It has blocking activity for ALPHA 1 ADRENERGIC RECEPTORS and, at higher doses, may function as a blocker of CALCIUM CHANNELS; it also has antioxidant properties. Carvedilol is used in the treatment of HYPERTENSION; ANGINA PECTORIS; and HEART FAILURE. It can also reduce the risk of death following MYOCARDIAL INFARCTION.
Broader concept
Entry terms
- 0K47UL67F2
- 107741-96-8 (+-)-isomer
- 118546-19-3 (14C-labeled)
- 2-Propanol, 1-(9H-carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)-
- 72956-09-3 (Carvedilol)
- 95093-99-5 (R)-isomer
- 95094-00-1 (S)-isomer
- GW13D96IND
- N6E193E020
- N9A00DJ8CM
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
0K47UL67F2
-
107741-96-8 (+-)-isomer
-
118546-19-3 (14C-labeled)
-
2-Propanol, 1-(9H-carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)-
-
72956-09-3 (Carvedilol)
-
95093-99-5 (R)-isomer
-
95094-00-1 (S)-isomer
-
GW13D96IND
-
N6E193E020
-
N9A00DJ8CM
URI
http://data.loterre.fr/ark:/67375/JVR-DG1SXTJT-P
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