Concept information
Preferred term
Dosage Compensation, Genetic
Type
-
mesh:Descriptor
Definition
- Genetic mechanisms that allow GENES to be expressed at a similar level irrespective of their GENE DOSAGE. This term is usually used in discussing genes that lie on the SEX CHROMOSOMES. Because the sex chromosomes are only partially homologous, there is a different copy number, i.e., dosage, of these genes in males vs. females. In DROSOPHILA, dosage compensation is accomplished by hypertranscription of genes located on the X CHROMOSOME. In mammals, dosage compensation of X chromosome genes is accomplished by random X CHROMOSOME INACTIVATION of one of the two X chromosomes in the female.
Broader concept
Narrower concepts
Entry terms
- Dosage Compensation (Genetics)
- Gene Dosage Compensation
Allowable Qualifier(s)
In other languages
-
French
-
Compensation de dosage (génétique)
-
Compensation de dosage génique
-
Compensation du dosage des gènes
URI
http://data.loterre.fr/ark:/67375/JVR-DHT89QVG-N
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