Concept information
Preferred term
Fanconi Anemia Complementation Group D2 Protein
Type
-
mesh:Descriptor
Definition
- A Fanconi anemia complementation group protein that undergoes mono-ubiquitination by FANCL PROTEIN in response to DNA DAMAGE. Also, in response to IONIZING RADIATION it can undergo PHOSPHORYLATION by ataxia telangiectasia mutated protein. Modified FANCD2 interacts with BRCA2 PROTEIN in a stable complex with CHROMATIN, and it is involved in DNA REPAIR by homologous RECOMBINATION.
Entry terms
- FANCD2 Protein
- Fanconi Anemia Group D2 Complementing Protein
- Fanconi Anemia Group D2 Protein
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Protéine du groupe D-2 de l'anémie de Fanconi
-
Protéine du groupe D-2 de la maladie de Fanconi
-
Protéine du groupe D2 de l'anémie de Fanconi
-
Protéine du groupe D2 de la maladie de Fanconi
-
Protéine FANC-D-2
-
Protéine FANC-D2
-
Protéine FANCD2
URI
http://data.loterre.fr/ark:/67375/JVR-DPL2Z27N-2
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