Concept information
Preferred term
Leukocyte L1 Antigen Complex
Type
-
mesh:Descriptor
Definition
- A member of the S-100 protein family that is present at high levels in the blood and interstitial fluid in several infectious, inflammatory, and malignant disorders, including rheumatoid arthritis, inflammatory bowel disease, and cystic fibrosis. It is a complex of a light chain (CALGRANULIN A) and a heavy chain (CALGRANULIN B). L1 binds calcium through an EF-hand motif, and has been shown to possess antimicrobial activity.
Broader concept
Narrower concepts
Entry terms
- 27E10 Antigen
- Calcium-Binding Myeloid Protein P8,14
- Calgranulin
- Calprotectin
- L1 Antigen
- Leukocyte L1 Protein
- Migratory Inhibitory Factor-Related Protein MRP
- Myelomonocytic Antigen L1
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Antigène 27E10
-
Antigène L1
-
Calgranuline
-
Calprotectine
-
Protéine L1 leucocytaire
-
Protéine MRP8/14
URI
http://data.loterre.fr/ark:/67375/JVR-DQ1RC7TL-W
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