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Pathological Conditions, Signs and Symptoms > Pathologic Processes > Chromosome Aberrations > Translocation, Genetic > Philadelphia Chromosome
... > Genetic Phenomena > Genetic Variation > Mutation > Chromosome Aberrations > Translocation, Genetic > Philadelphia Chromosome
Genetic Phenomena > Mutagenesis > Translocation, Genetic > Philadelphia Chromosome
... > Genetic Phenomena > Genetic Structures > Chromosomes > Chromosomes, Mammalian > Chromosomes, Human > Chromosomes, Human, 21-22 and Y > Chromosomes, Human, Pair 22 > Philadelphia Chromosome
... > Cells > Cellular Structures > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Organelles > Cell Nucleus > Cell Nucleus Structures > Intranuclear Space > Chromosomes > Chromosomes, Mammalian > Chromosomes, Human > Chromosomes, Human, 21-22 and Y > Chromosomes, Human, Pair 22 > Philadelphia Chromosome
... > Fluids and Secretions > Body Fluids > Body Fluid Compartments > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Organelles > Cell Nucleus > Cell Nucleus Structures > Intranuclear Space > Chromosomes > Chromosomes, Mammalian > Chromosomes, Human > Chromosomes, Human, 21-22 and Y > Chromosomes, Human, Pair 22 > Philadelphia Chromosome
... > Tissues > Body Fluid Compartments > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Organelles > Cell Nucleus > Cell Nucleus Structures > Intranuclear Space > Chromosomes > Chromosomes, Mammalian > Chromosomes, Human > Chromosomes, Human, 21-22 and Y > Chromosomes, Human, Pair 22 > Philadelphia Chromosome
... > Genetic Phenomena > Genetic Structures > Chromosomes > Chromosomes, Mammalian > Chromosomes, Human > Chromosomes, Human, 6-12 and X > Chromosomes, Human, Pair 9 > Philadelphia Chromosome
... > Cells > Cellular Structures > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Organelles > Cell Nucleus > Cell Nucleus Structures > Intranuclear Space > Chromosomes > Chromosomes, Mammalian > Chromosomes, Human > Chromosomes, Human, 6-12 and X > Chromosomes, Human, Pair 9 > Philadelphia Chromosome
... > Fluids and Secretions > Body Fluids > Body Fluid Compartments > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Organelles > Cell Nucleus > Cell Nucleus Structures > Intranuclear Space > Chromosomes > Chromosomes, Mammalian > Chromosomes, Human > Chromosomes, Human, 6-12 and X > Chromosomes, Human, Pair 9 > Philadelphia Chromosome
... > Tissues > Body Fluid Compartments > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Organelles > Cell Nucleus > Cell Nucleus Structures > Intranuclear Space > Chromosomes > Chromosomes, Mammalian > Chromosomes, Human > Chromosomes, Human, 6-12 and X > Chromosomes, Human, Pair 9 > Philadelphia Chromosome

Preferred term

Philadelphia Chromosome  

Type

  • mesh:Descriptor

Definition

  • An aberrant form of human CHROMOSOME 22 characterized by translocation of the distal end of chromosome 9 from 9q34, to the long arm of chromosome 22 at 22q11. It is present in the bone marrow cells of 80 to 90 per cent of patients with chronic myelocytic leukemia (LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE).

Broader concept

Related concepts

Entry terms

  • Ph 1 Chromosome
  • Ph1 Chromosome

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-DQC1FZH3-C

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RDF/XML TURTLE JSON-LD Created 5/3/85, last modified 6/28/16