: MeSH: Giant Cells, Foreign-Body

Cells > Connective Tissue Cells > Macrophages > Giant Cells, Foreign-Body

Hemic and Immune Systems > Immune System > Mononuclear Phagocyte System > Macrophages > Giant Cells, Foreign-Body

Cells > Phagocytes > Macrophages > Giant Cells, Foreign-Body

Hemic and Immune Systems > Immune System > Phagocytes > Macrophages > Giant Cells, Foreign-Body

Cells > Myeloid Cells > Macrophages > Giant Cells, Foreign-Body

Cells > Giant Cells > Giant Cells, Foreign-Body

Giant Cells, Foreign-Body

Multinucleated cells (fused macrophages), characteristic of granulomatous inflammation, which form around exogenous material in the skin. They are similar in appearance to Langhans giant cells (GIANT CELLS, LANGHANS), but foreign-body giant cells have more abundant chromatin and their nuclei are scattered in an irregular pattern in the cytoplasm.

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