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Preferred term

Hypoaldosteronism  

Type

  • mesh:Descriptor

Definition

  • A congenital or acquired condition of insufficient production of ALDOSTERONE by the ADRENAL CORTEX leading to diminished aldosterone-mediated synthesis of Na(+)-K(+)-EXCHANGING ATPASE in renal tubular cells. Clinical symptoms include HYPERKALEMIA, sodium-wasting, HYPOTENSION, and sometimes metabolic ACIDOSIS. A selective aldosterone deficiency resulting from diminished RENIN-generated ANGIOTENSIN II, a key stimulus to aldosterone secretion. Previously, it was called type IV renal tubular acidosis.

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URI

http://data.loterre.fr/ark:/67375/JVR-DXRZC5X7-N

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RDF/XML TURTLE JSON-LD Created 3/13/87, last modified 7/5/06