Skip to main content

Medical Subject Headings (thesaurus)

Search from vocabulary

align
annotate
download

Concept information

Nervous System Diseases > Demyelinating Diseases > Leukoencephalopathy, Progressive Multifocal
Infections > Virus Diseases > Slow Virus Diseases > Leukoencephalopathy, Progressive Multifocal
Infections > Virus Diseases > Central Nervous System Viral Diseases > Encephalitis, Viral > Leukoencephalopathy, Progressive Multifocal
... > Nervous System Diseases > Central Nervous System Diseases > Central Nervous System Infections > Central Nervous System Viral Diseases > Encephalitis, Viral > Leukoencephalopathy, Progressive Multifocal
Infections > Central Nervous System Infections > Central Nervous System Viral Diseases > Encephalitis, Viral > Leukoencephalopathy, Progressive Multifocal
... > Nervous System Diseases > Neuroinflammatory Diseases > Encephalitis > Infectious Encephalitis > Encephalitis, Viral > Leukoencephalopathy, Progressive Multifocal
... > Pathological Conditions, Signs and Symptoms > Pathologic Processes > Inflammation > Neuroinflammatory Diseases > Encephalitis > Infectious Encephalitis > Encephalitis, Viral > Leukoencephalopathy, Progressive Multifocal
... > Nervous System Diseases > Central Nervous System Diseases > Brain Diseases > Encephalitis > Infectious Encephalitis > Encephalitis, Viral > Leukoencephalopathy, Progressive Multifocal
... > Nervous System Diseases > Central Nervous System Diseases > Central Nervous System Infections > Infectious Encephalitis > Encephalitis, Viral > Leukoencephalopathy, Progressive Multifocal
Infections > Central Nervous System Infections > Infectious Encephalitis > Encephalitis, Viral > Leukoencephalopathy, Progressive Multifocal
Infections > Virus Diseases > DNA Virus Infections > Polyomavirus Infections > Leukoencephalopathy, Progressive Multifocal
Nervous System Diseases > Central Nervous System Diseases > Brain Diseases > Leukoencephalopathies > Leukoencephalopathy, Progressive Multifocal

Preferred term

Leukoencephalopathy, Progressive Multifocal  

Type

  • mesh:Descriptor

Definition

  • An opportunistic viral infection of the central nervous system associated with conditions that impair cell-mediated immunity (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME and other IMMUNOLOGIC DEFICIENCY SYNDROMES; HEMATOLOGIC NEOPLASMS; IMMUNOSUPPRESSION; and COLLAGEN DISEASES). The causative organism is JC Polyomavirus (JC VIRUS) which primarily affects oligodendrocytes, resulting in multiple areas of demyelination. Clinical manifestations include DEMENTIA; ATAXIA; visual disturbances; and other focal neurologic deficits, generally progressing to a vegetative state within 6 months. (From Joynt, Clinical Neurology, 1996, Ch26, pp36-7)

Broader concept

Entry terms

  • Encephalitis, JC Polyomavirus
  • JC Polyomavirus Encephalopathy
  • Progressive Multifocal Leukoencephalopathy

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-F0D2GS3N-2

Download this concept:

RDF/XML TURTLE JSON-LD Created 1/1/99, last modified 6/30/21