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... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structural Elements > Amino Acid Motifs > Helix-Loop-Helix Motifs > Helix-Turn-Helix Motifs
... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structure, Secondary > Amino Acid Motifs > Helix-Loop-Helix Motifs > Helix-Turn-Helix Motifs

Preferred term

Helix-Turn-Helix Motifs  

Type

  • mesh:Descriptor

Definition

  • The first DNA-binding protein motif to be recognized. Helix-turn-helix motifs were originally identified in bacterial proteins but have since been found in hundreds of DNA-BINDING PROTEINS from both eukaryotes and prokaryotes. They are constructed from two alpha helices connected by a short extended chain of amino acids, which constitute the "turn." The two helices are held at a fixed angle, primarily through interactions between the two helices. (From Alberts et al., Molecular Biology of the Cell, 3d ed, p408-9)

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Entry terms

  • HTH Motifs
  • Motifs, Helix-Turn-Helix

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URI

http://data.loterre.fr/ark:/67375/JVR-F2G2F0H3-P

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