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Concept information

... > Organic Chemicals > Lactones > Polyketides > Macrolides > Sirolimus > Everolimus
... > Polycyclic Compounds > Macrocyclic Compounds > Polyketides > Macrolides > Sirolimus > Everolimus
... > Chemical Actions and Uses > Pharmacologic Actions > Therapeutic Uses > Antineoplastic Agents > MTOR Inhibitors > Everolimus
... > Chemical Actions and Uses > Pharmacologic Actions > Molecular Mechanisms of Pharmacological Action > Enzyme Inhibitors > Protein Kinase Inhibitors > MTOR Inhibitors > Everolimus
... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Immunologic Factors > Immunosuppressive Agents > MTOR Inhibitors > Everolimus

Preferred term

Everolimus  

Type

  • mesh:Descriptor

Definition

  • A derivative of sirolimus and an inhibitor of TOR SERINE-THREONINE KINASES. It is used to prevent GRAFT REJECTION in heart and kidney transplant patients by blocking cell proliferation signals. It is also an ANTINEOPLASTIC AGENT.

Broader concept

Entry terms

  • 40-O-(2-hydroxyethyl)-rapamycin
  • 9HW64Q8G6G
  • SDZ RAD
  • SDZ-RAD

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-F4Z32892-K

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RDF/XML TURTLE JSON-LD Created 7/1/15, last modified 7/1/21