Concept information
Preferred term
Quinacrine
Type
-
mesh:Descriptor
Definition
- An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
Broader concept
Narrower concepts
Entry terms
- 130-42-7 (mono-HCl)
- 130-43-8 (monomesylate)
- 139345-02-1 ((S)-isomer)
- 139345-03-2 ((R)-isomer)
- 1,4-Pentanediamine, N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-
- 316-05-2 (dimesylate)
- 56100-41-5 ((S)-isomer, di-HCl)
- 56100-42-6 ((R)-isomer, di-HCl)
- 6151-30-0 (di-HCl, di-H2O)
- 66777-81-9 ((+-)-isomer)
- 69-05-6 (di-HCl)
- 78901-94-7 (monoacetate)
- 83-89-6 (Quinacrine)
- Atebrin
- G6242H2NAA
- H0C805XYDE
- Mepacrine
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
1,4-Pentanediamine, N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-
-
130-42-7 (mono-HCl)
-
130-43-8 (monomesylate)
-
139345-02-1 ((S)-isomer)
-
139345-03-2 ((R)-isomer)
-
316-05-2 (dimesylate)
-
56100-41-5 ((S)-isomer, di-HCl)
-
56100-42-6 ((R)-isomer, di-HCl)
-
6151-30-0 (di-HCl, di-H2O)
-
66777-81-9 ((+-)-isomer)
-
69-05-6 (di-HCl)
-
78901-94-7 (monoacetate)
-
83-89-6 (Quinacrine)
-
G6242H2NAA
-
H0C805XYDE
URI
http://data.loterre.fr/ark:/67375/JVR-F5871PQ0-0
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