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Concept information

Preferred term

alpha-MSH  

Type

  • mesh:Descriptor

Definition

  • A 13-amino acid peptide derived from proteolytic cleavage of ADRENOCORTICOTROPIC HORMONE, the N-terminal segment of ACTH. ACTH (1-13) is amidated at the C-terminal to form ACTH (1-13)NH2 which in turn is acetylated to form alpha-MSH in the secretory granules. Alpha-MSH stimulates the synthesis and distribution of MELANIN in MELANOCYTES in mammals and MELANOPHORES in lower vertebrates.

Entry terms

  • 581-05-5
  • Acetylated ACTH (1-13)NH2
  • alpha Intermedin
  • alpha-Melanocyte-Stimulating Hormone
  • alpha-Melanotropin
  • MSH, alpha

Pharmacological Action(s)

In other languages

  • French

  • 581-05-5
  • alpha-Melanotropin
  • alpha-MSH
  • Hormone mélanostimulante alpha
  • Hormone stimulant les mélanocytes alpha
  • Mélanotropine alpha
  • MSH-alpha

URI

http://data.loterre.fr/ark:/67375/JVR-F80ZCC33-C

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