Concept information
Preferred term
Solute Carrier Organic Anion Transporter Family Member 1B3
Type
-
mesh:Descriptor
Definition
- A sodium-independent organic anion transporter that functions in the uptake of various drugs and endogenous compounds including ESTRADIOL; TAUROCHOLATE; LEUKOTRIENE C4; and METHOTREXATE. It also functions in clearing BILE ACIDS and organic anions from the liver. Mutations in the SLCO1B3 gene are associated with Rotor Type HYPERBILIRUBINEMIA.
Entry terms
- Liver-Specific Organic Anion Transporter-2
- OATP1B3 Protein
- OATP8 Protein
- SLC21A8 Protein
- SLCO1B3 Protein
- Solute Carrier Family 21 Member 8 Protein
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Membre-8 de la famille-21 de transporteurs de solutés
-
Protéine OATP1B3
-
Protéine OATP8
-
Protéine SLC21A8
-
Protéine SLCO1B3
-
Transporteur-2 d'anions organiques spécifique du foie
URI
http://data.loterre.fr/ark:/67375/JVR-F981D93F-X
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