Concept information
Preferred term
Chlorambucil
Type
-
mesh:Descriptor
Definition
- A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Broader concept
Narrower concepts
Entry terms
- 18D0SL7309
- 305-03-3 (Chlorambucil)
- 4-(Bis(2-chloroethyl)amino)benzenebutanoic Acid
- Benzenebutanoic acid, 4-(bis(2-chloroethyl)amino)-
- Chloraminophene
- Chlorbutin
- N,N-Di-(2-chloroethyl)-p-aminophenylbutyric Acid
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
18D0SL7309
-
305-03-3 (Chlorambucil)
-
Benzenebutanoic acid, 4-(bis(2-chloroethyl)amino)-
URI
http://data.loterre.fr/ark:/67375/JVR-FFMPZ4R2-J
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