Concept information
Preferred term
ADAMTS5 Protein
Type
-
mesh:Descriptor
Definition
- An ADAMTS protease that contains two C-terminal thrombospondin (TS) motifs. It functions primarily as an aggrecanase, cleaving AGGRECAN in CARTILAGE, and may be involved in the destruction of aggrecan in ARTHRITIS.
Broader concept
Entry terms
- ADAMTS11 Protein
- ADAMTS5 Protease
- ADAMTS-5 Protein
- A Disintegrin And Metalloproteinase With Thrombospondin Motifs 5 Protein
- Aggrecanase-2
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Aggrécanase-2
-
Métalloprotéase-5 contenant un domaine désintégrine et des motifs thrombospondines
-
Métalloprotéinase-5 contenant un domaine désintégrine et des motifs thrombospondines
-
Protéase ADAMTS5
-
Protéine ADAMTS-5
-
Protéine ADAMTS11
-
Protéine-5 contenant des domaines disintégrine et métalloprotéase et des motifs thrombospondines
-
Protéine-5 contenant des domaines disintégrine et métalloprotéinase et des motifs thrombospondines
URI
http://data.loterre.fr/ark:/67375/JVR-FFN75JCX-9
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