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... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Oncogene Proteins > Proto-Oncogene Proteins > KRIT1 Protein
Amino Acids, Peptides, and Proteins > Proteins > Nerve Tissue Proteins > Microtubule-Associated Proteins > KRIT1 Protein
... > Amino Acids, Peptides, and Proteins > Proteins > Cytoskeletal Proteins > Microtubule Proteins > Microtubule-Associated Proteins > KRIT1 Protein
... > Technology, Industry, and Agriculture > Manufactured Materials > Biomedical and Dental Materials > Polymers > Biopolymers > Microtubule Proteins > Microtubule-Associated Proteins > KRIT1 Protein
... > Chemical Actions and Uses > Specialty Uses of Chemicals > Biomedical and Dental Materials > Polymers > Biopolymers > Microtubule Proteins > Microtubule-Associated Proteins > KRIT1 Protein
... > Macromolecular Substances > Polymers > Biopolymers > Microtubule Proteins > Microtubule-Associated Proteins > KRIT1 Protein

Preferred term

KRIT1 Protein  

Type

  • mesh:Descriptor

Definition

  • A microtubule-associated protein consisting of four ANKYRIN REPEATS and a C-terminal FERM DOMAIN. It links the CYTOSKELETON to CELL JUNCTIONS via integrin cytoplasmic domain-associated protein-1 and plays an important role in regulating cell proliferation and integrity of endothelial cell junctions. It is also involved in REACTIVE OXYGEN SPECIES metabolism. Mutations in the KRIT1 gene are associated with type I CEREBRAL CAVERNOUS MALFORMATIONS.

Broader concept

Entry terms

  • Cerebral Cavernous Malformations 1 Protein
  • Krev Interaction Trapped Protein 1

Allowable Qualifier(s)

In other languages

  • Protéine KRIT1

    French

  • Protéine associée avec les malformations caverneuses cérébrales de type 1

URI

http://data.loterre.fr/ark:/67375/JVR-FHZ0LQ0S-4

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RDF/XML TURTLE JSON-LD Created 7/11/17, last modified 6/29/17