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Concept information

Preferred term

RNA 5' Terminal Oligopyrimidine Sequence  

Type

  • mesh:Descriptor

Definition

  • A regulatory sequence found in the 5' terminal regions of a variety of RNA species. The sequence starts with a CYTIDINE, which is followed by a stretch of 5 to 15 PYRIMIDINE NUCLEOTIDES. Messenger RNA that contains the 5' Terminal Oligo Pyrimidine tract is often referred to as 5' TOP mRNA. The sequence acts as a translational regulator and has been found in mRNAs for PEPTIDE ELONGATION FACTORS and RIBOSOMAL PROTEINS.

Entry terms

  • 5' TOP Sequence
  • RNA 5' Terminal Oligopyrimidine Regulatory Sequence

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-FK2NWL5P-9

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RDF/XML TURTLE JSON-LD Created 7/3/02, last modified 7/9/13