: MeSH: Positive Regulatory Domain I-Binding Factor 1

... > Transferases > One-Carbon Group Transferases > Methyltransferases > Protein Methyltransferases > Positive Regulatory Domain I-Binding Factor 1

Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Repressor Proteins > Positive Regulatory Domain I-Binding Factor 1

Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Repressor Proteins > Positive Regulatory Domain I-Binding Factor 1

Positive Regulatory Domain I-Binding Factor 1

A transcriptional repressor protein that contains an N-terminal PR-SET domain, four C-terminal CYS2-HIS2 ZINC FINGERS, and binds the PRDI element in the INTERFERON-BETA gene. It has methyltransferase activity and mediates gene transcription in tissue-specific innate and adaptive immune lymphocyte T-CELLS, repressing expression of proteins that promote exit of these tissue-specific T-cell populations from non-lymphoid organs.

http://data.loterre.fr/ark:/67375/JVR-FPS03PTK-9

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