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... > Genetic Phenomena > Genetic Structures > Genome > Genome Components > Genes > Genes, Neoplasm > Genes, Tumor Suppressor > Genes, Retinoblastoma
Genetic Phenomena > Inheritance Patterns > Genes, Recessive > Genes, Tumor Suppressor > Genes, Retinoblastoma
... > Genetic Phenomena > Genetic Structures > Genome > Genome Components > Genes > Genes, Recessive > Genes, Tumor Suppressor > Genes, Retinoblastoma

Preferred term

Genes, Retinoblastoma  

Type

  • mesh:Descriptor

Definition

  • Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma.

Broader concept

Related concepts

Entry terms

  • Genes, Rb
  • Rb Genes
  • Retinoblastoma Genes

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URI

http://data.loterre.fr/ark:/67375/JVR-FW0676CD-5

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RDF/XML TURTLE JSON-LD Created 5/7/90, last modified 6/25/10