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... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Amino Acid Sequence > Immunoglobulin Variable Region > Immunoglobulin Joining Region
... > Information Science > Information Services > Documentation > Molecular Sequence Data > Amino Acid Sequence > Immunoglobulin Variable Region > Immunoglobulin Joining Region
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Serum Globulins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Immunoglobulin Variable Region > Immunoglobulin Joining Region
... > Amino Acids, Peptides, and Proteins > Proteins > Globulins > Serum Globulins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Immunoglobulin Variable Region > Immunoglobulin Joining Region
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Immunoglobulin Variable Region > Immunoglobulin Joining Region
... > Amino Acids, Peptides, and Proteins > Peptides > Peptide Fragments > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Immunoglobulin Variable Region > Immunoglobulin Joining Region

Preferred term

Immunoglobulin Joining Region  

Type

  • mesh:Descriptor

Definition

  • A segment of the immunoglobulin heavy chains, encoded by the IMMUNOGLOBULIN HEAVY CHAIN GENES in the J segment where, during the maturation of B-LYMPHOCYTES; the gene segment for the variable region upstream is joined to a constant region gene segment downstream. The exact position of joining of the two gene segments is variable and contributes to ANTIBODY DIVERSITY. It is distinguished from the IMMUNOGLOBULIN J CHAINS; a separate polypeptide that serves as a linkage piece in polymeric IGA or IGM.

Broader concept

Related concepts

Entry terms

  • Joining Region, Ig

Allowable Qualifier(s)

Pharmacological Action(s)

In other languages

  • Région J d'immunoglobuline

    French

  • Région charnière d'immunoglobuline
  • Région charnière des immunoglobulines
  • Région jonction d'immunoglobuline
  • Séquence jonction d'immunoglobuline

URI

http://data.loterre.fr/ark:/67375/JVR-FWZW3LMT-X

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RDF/XML TURTLE JSON-LD Created 5/11/87, last modified 6/25/10