Concept information
Preferred term
Erythromycin Estolate
Type
-
mesh:Descriptor
Definition
- A macrolide antibiotic, produced by Streptomyces erythreus. It is the lauryl sulfate salt of the propionic ester of erythromycin. This erythromycin salt acts primarily as a bacteriostatic agent. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
Broader concept
Entry terms
- 3521-62-8 (Erythromycin Estolate)
- Erythromycin, 2'-propanoate, dodecyl sulfate (salt)
- Erythromycin Propionate Dodecyl Sulfate
- Erythromycin Propionate Lauryl Sulfate
- Erythromycin Propionate Monododecyl Sulfate
- XRJ2P631HP
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
3521-62-8 (Erythromycin Estolate)
-
Erythromycin, 2'-propanoate, dodecyl sulfate (salt)
-
Estolate d'érythromycine
-
XRJ2P631HP
URI
http://data.loterre.fr/ark:/67375/JVR-FZPTH164-Z
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