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... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Tyrosine Phosphatases > Protein Tyrosine Phosphatases, Non-Receptor > Protein Tyrosine Phosphatase, Non-Receptor Type 12
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Tyrosine Phosphatases > Protein Tyrosine Phosphatases, Non-Receptor > Protein Tyrosine Phosphatase, Non-Receptor Type 12
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Phosphoric Monoester Hydrolases > Protein Tyrosine Phosphatases > Protein Tyrosine Phosphatases, Non-Receptor > Protein Tyrosine Phosphatase, Non-Receptor Type 12

Preferred term

Protein Tyrosine Phosphatase, Non-Receptor Type 12  

Type

  • mesh:Descriptor

Definition

  • A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of a N-terminal catalytic domain and a large C-terminal domain that is enriched in PROLINE, GLUTAMIC ACID, SERINE, and THREONINE residues (PEST sequences). The phosphatase subtype is ubiquitously expressed and implicated in the regulation of a variety of biological processes such as CELL MOVEMENT; CYTOKINESIS; focal adhesion disassembly; and LYMPHOCYTE ACTIVATION.

Broader concept

Entry terms

  • PEP Protein Tyrosine Phosphatase
  • PEP PTPase
  • PEST-Enriched Phosphatase
  • PTP-PEST

Allowable Qualifier(s)

In other languages

  • Protein Tyrosine Phosphatase, Non-Receptor Type 12

    French

  • PEP PTPase
  • PEST-Enriched Phosphatase
  • Protéine PTP-PEST
  • Protéine tyrosine phosphatase non-réceptrice de type 12
  • Protéine tyrosine phosphatase PEP
  • Protéine-tyrosine phosphatase non-réceptrice de type 12

URI

http://data.loterre.fr/ark:/67375/JVR-G0QM2DVR-4

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