Concept information
Preferred term
Metabolic Detoxication, Phase II
Type
-
mesh:Descriptor
Definition
- The conjugation of exogenous substances with various hydrophilic substituents to form water soluble products that are excretable in URINE. Phase II modifications include GLUTATHIONE conjugation; ACYLATION; and AMINATION. Phase II enzymes include GLUTATHIONE TRANSFERASE and GLUCURONOSYLTRANSFERASE. In a sense these reactions detoxify phase I reaction products.
Broader concept
Entry terms
- Metabolic Detoxication, Conjugative
- Metabolic Detoxification, Phase II
- Phase II Detoxification
Allowable Qualifier(s)
In other languages
-
French
-
Détoxication métabolique de phase II
-
Détoxication par conjugaison
-
Détoxification de phase II
-
Détoxification métabolique de phase II
-
Détoxification par conjugaison
URI
http://data.loterre.fr/ark:/67375/JVR-G1QBM01V-D
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