Concept information
Preferred term
PTB-Associated Splicing Factor
Type
-
mesh:Descriptor
Definition
- An RNA splicing factor that also binds DNA. It is essential for pre-mRNA spicing in the formation of early SPLICEOSOMES and catalytic step II. It binds specifically to polypyrimidine tracts in INTRONS and is involved in the regulation of ALTERNATIVE SPLICING by SIGNAL TRANSDUCTION PATHWAYS.
Broader concept
Entry terms
- Polypyrimidine Tract-Binding Protein-Associated Splicing Factor
- PSF Splicing Factor
- SFPQ Protein
- Splicing Factor Proline-Glutamine Rich Protein
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
In other languages
-
French
-
Facteur d'épissage associé à la protéine fixant les séquences polypyrimidiques
-
Facteur d'épissage associé à la protéine liant les séquences polypyrimidiques
-
Facteur d'épissage associé à la protéine reconnaissant les séquences polypyrimidiques
-
Facteur d'épissage PSF
-
Facteur protéique d'épissage riche en proline et glutamine
-
Protéine SFPQ
URI
http://data.loterre.fr/ark:/67375/JVR-G50HSF8D-G
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